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Knowledge Base (Clinicians)
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Clozapine
Tag: Clozapine
Knowledge Base (Clinicians)
109 result(s) found.
Persistent psychotic symptoms in schizophrenia
Management of tardive movement disorders
Salivation side effect of clozapine (sialorrhea)
Sedation side effect of clozapine
Myocarditis side effect of clozapine
Constipation side effect of clozapine
How do I interpret clozapine or norclozapine blood, serum or plasma levels; What do these mean?
Clozapine blood count monitoring
Seizure side effect of clozapine
When to use clozapine
Orthostatic hypotension due to clozapine
Tachycardia side effect of clozapine
How does one dose or titrate clozapine dosage when starting on this medication?
Is weight gain a problem with clozapine, and what can be done?
How does clozapine work and how is it different from other medications?
Why is clozapine not the first medication chosen to treat schizophrenia for everyone?
What is the difference between the older and newer antipsychotic medications?
What is the Sequential Intercept Model?
What is clozapine REMS?
Why are many of the medications used to treat schizophrenia today the same ones that were used 15-30 years ago?
Clozapine Underutilization: Addressing the Barriers
The Clozapine Risk Evaluation and Mitigation Strategy (REMS) Program Modification
Second-Generation (atypical) Antipsychotics – Medication Fact Sheets
Vision side effects of clozapine
What can I do if it is difficult or risky to start a patient on clozapine? Should patients be started on clozapine in the hospital?
Should I be concerned if eosinophils are low or high with clozapine or there is eosinophilia?
What about anemia in people with serious mental illness, and should I be concerned about ordering blood tests?
What are the issues regarding families and caregivers supporting clozapine treatment?
Are there any contraindications or reasons a patient cannot be considered for clozapine? Can a patient with myocarditis or severe neutropenia be rechallenged and take clozapine again?
What is Benign Ethnic Neutropenia and does it relate to low clozapine white counts?
What should be done if the clozapine treatment of a patient is interrupted, or they do not take their clozapine for a few days or longer?
What can clinicians do when individuals have either a partial or no response to clozapine?
Is there anything I should know about smoking, tobacco or nicotine and clozapine?
Have any patient tracking forms been developed for clozapine?
What are approaches to treatment-resistant depression in patients with bipolar disorder?
Should I be concerned about Electroconvulsive Therapy (ECT) in the context of an intracranial mass or lesion?
A patient is moving to a new location and needs to find a new prescriber or pharmacist for clozapine. What information is available on this?
What is the evidence regarding combining multiple antipsychotic medications?
What is known about research on antipsychotic medications and clozapine for schizophrenia in children and adolescents?
What are the issues regarding starting clozapine in a patient with structural heart disease, such as cardiomyopathy or cardiac valve disease?
What metabolic monitoring is appropriate when patients are taking clozapine? Should we monitor weight, labs or vital signs?
What drug-drug medication interactions are important when starting or prescribing clozapine?
What should I consider if a clozapine or norclozapine blood, plasma or serum level is surprisingly high?
Interventions for Adult Offenders With Serious Mental Illness
How do I start a clozapine clinic or system, or start to prescribe clozapine?
Are there newer technologies, such as point of care (POC) tests or finger stick blood tests, that can help ease the monitoring burden and facilitate management of clozapine?
How should I transition, taper or discontinue an existing antipsychotic medication when starting clozapine?
Can botulinum toxin (Botox) be used for salivation caused by clozapine?
What can cause blood or serum levels of clozapine to change or vary on a given dosage?
Clozapine for Schizophrenia: A Comparison of the States
Clozapine Center of Excellence
Is clozapine more effective than other antipsychotic medications in individuals with treatment-resistant psychosis?
What should be done if hepatic liver function tests are increased with clozapine treatment?
What is known about use of clozapine for schizophrenia in children and adolescents (people younger than 18 years old)?
Are there examples of monitoring protocols or tracking log forms that could be used when starting clozapine?
What if a patient has clozapine side effects and is found to have a surprisingly high clozapine level?
When prescribing, what should I consider regarding doses of antipsychotic medications, oral or long-acting injectable medications?
Is it possible to use fluvoxamine to improve the tolerability or metabolic side effects of clozapine?
Can clozapine cause Obsessive Compulsive Disorder (OCD), and what can be done about this?
Second-Generation (atypical) Antipsychotics – Medication Fact Sheets (Spanish Version)
What can be done if a patient taking clozapine is travelling to a foreign country?
What are approaches for treating or managing anxiety in patients with schizophrenia who are taking clozapine?
What should be considered regarding concurrent psychiatric medications, medications a patient is taking while considering or starting clozapine?
What is known about norclozapine blood levels for patients taking clozapine?
In treating Indian American populations with SMI, are there any unique factors that must be considered?
Is it possible to plan for continuation of clozapine during emergencies (such as coronavirus COVID-19 pandemic, infectious disease, hurricanes, tornadoes, earthquakes, rioting) that destroy infrastructure or limit travel, or other issues that prevent a patient from coming to a clinic or laboratory for necessary assessments or blood monitoring?
During the COVID-19 pandemic, can pharmacies dispense clozapine without an absolute neutrophil count (ANC) blood test result?
Can clozapine cause problems with urine or urination, such as incontinence (enuresis) or urinary retention?
Can clozapine cause priapism, and if so what can be done?
Is there an association between clozapine and venous thromboembolism?
Does clozapine have a protective effect for suicide in people with schizophrenia or schizoaffective disorder?
Clozapine & LAI Virtual Forum – August 2020 (Video) – Clozapine hematologic monitoring and COVID-19
Clozapine & LAI Virtual Forum – September 2020 (Video) – Antipsychotic conversion to LAIs
Is clozapine safe to continue during breastfeeding?
Clozapine & LAI Virtual Forum – October 2020 (Video) – Understanding and mitigating clozapine-induced myocarditis
Clozapine & LAI Virtual Forum – December 2020 (Video) – Pharmacologic and psychosocial strategies for a partial Clozapine response
Clozapine & LAI Virtual Forum – February 2021 (Video) – Clozapine titrations: new starts and re-titrating after treatment interruption
Needs Assessments on Technical Assistance and Education
Clozapine & LAI Virtual Forum – April 2021 (Video) – Clozapine and Sialorrhea
Clozapine & LAI Virtual Forum – June 2021 (Video) – Clozapine and treatment of cardiometabolic side effects
Clozapine & LAI Virtual Forum – August 2021 (Video) – Case Study: Clozapine and Cognition
Comparative Effectiveness of Antipsychotics for Risk of Attempted or Completed Suicide Among Persons With Schizophrenia
Ask About Clozapine – Patient Handout
Clozapine & LAI Virtual Forum – October 2021 (Video) – Keeping up with Clozapine REMS changes
Clozapine REMS Program Updates: A Guide for Prescribers and Pharmacists
Clozapine Monitoring Protocol
Clozapine & LAI Virtual Forum – December 2021 (Video) – Initial impressions of Clozapine REMS: Troubleshooting and brainstorming new workflows
A Survey of Personnel and Services Offered in 32 Outpatient US Clozapine Clinics
Talking to Individuals and Families About Clozapine
How do you present clozapine to a person who might benefit from it?
Recommendations for Managing Patients on Pimozide, Lurasidone, or Clozapine During Treatment with a 5-Day Course of Paxlovid
Can clozapine cause cardiomyopathy?
Clozapine & LAI Virtual Forum – March 2022 (Video) – Continued troubleshooting on Clozapine REMS: Minimizing treatment disruptions and optimizing workflows
Clozapine & LAI Virtual Forum – June 2022 (Video) – Benign Ethnic Neutropenia (BEN)
Is there a relationship between long-term clozapine use and hematological malignancies?
Antipsychotics and heat-related illnesses
Vigilance and Monitoring for Clozapine Toxicity During COVID-19 Infection and Recommendations for Management
Clozapine & LAI Virtual Forum – September 2022 (Video) – Appropriate use of weight loss medication with clozapine with a focus on GLP-1 agonists
Clozapine & LAI Virtual Forum – November 2022 (Video) – Management of clozapine-induced constipation
FDA exercises additional enforcement discretion for Clozapine REMS (Updated November 2, 2022)
Clozapine & LAI Virtual Forum – January 2023 (Video) – OCD in patients taking clozapine
Clozapine & LAI Virtual Forum – March 2023 (Video) – Managing Sedation Due to Clozapine
Clozapine & LAI Virtual Forum – May 2023 (Video) – Management of Clozapine-Induced Sialorrhea: Highlighting Botulinum Toxin
Clozapine & LAI Virtual Forum – August 2023 (Video) – Non-antipsychotic, pharmacologic augmentation strategies to partial responders on clozapine
Is there only one best titration standard for starting clozapine?
Is clozapine a medication that should only be used when all other medications have failed?
First-line Treatments for Clozapine-induced Drooling (Videos & Handouts)
Clozapine & LAI Virtual Forum – January 2024 (Video) – Clozapine’s Unique Role for Managing Aggressive Behavior
Myth vs. Fact on Serious Mental Illness (Infographics)